Gene interactions and pathways from curated databases and text-mining

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CCR7 — IFNG

Text-mined interactions from Literome

Dauer et al., J Immunol 2003 (Second Messenger Systems) : FastDC expressed mature DC surface markers as well as chemokine receptor 7 and secreted IL-12 ( p70 ) upon CD40 ligation in the presence of IFN-gamma
Wan et al., Blood 2004 : The induction of interferon-gamma-inducible protein 10 ( IP-10 ) secretion by Hsp70L1 is not shared by Hsp70, and other functional differences include more potent stimulation of DC IL-12p70, CC-chemokine, and CCR7 and CXCR4 expression by Hsp70L1. Immunization of mice with the hybrid peptide Hsp70L1-ovalbumin ( OVA ) ( 257-264 ) induces an OVA ( 257-264 ) -specific Th1 response and cytotoxic T lymphocyte ( CTL ) that results in significant inhibition of E.G7-OVA tumor growth
Noor et al., Infect Immun 2010 (Toxoplasmosis) : Adoptive-transfer experiments revealed that expression of CCR7 on the T-cell compartment alone is sufficient to enable T-cell priming, increase IFN-gamma production, and allow the survival of CCR7 ( -/- ) mice
Zella et al., Blood 1998 : Interferon-gamma increases expression of chemokine receptors CCR1, CCR3 , and CCR5, but not CXCR4 in monocytoid U937 cells