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APOB — GRAP2
Text-mined interactions from Literome
Relou et al., Thromb Haemost 2002
(MAP Kinase Signaling System) :
Antibody 4G3 disturbs
apoB100 binding to the classical apoB/E receptor and
inhibits LDL induced
p38MAPK activation, whereas an antibody against a distal domain on apoB 100 has no effect
Mehta et al., Cardiovasc Res 2004
:
Ox-LDL also
enhanced the activity of
p38MAPK in HCAECs, and aspirin blocked this effect of ox-LDL ( P < 0.01 )
Dobreva et al., Biol Chem 2005
:
Elevated
low-density lipoprotein (LDL) levels
induce activation of the
p38 mitogen activated protein kinase ( MAPK ), a stress activated protein kinase potentially participating in the development of atherosclerosis
Hakala et al., Arterioscler Thromb Vasc Biol 2006
(Inflammation) :
H-LDL induced rapid phosphorylation of the
p38 mitogen activated protein kinase ( MAPK ), nuclear translocation of 2 transcription factors, nuclear factor kappaB (NF-kappaB) and activator protein 1 (AP-1), and time dependent secretion of IL-8 from the macrophages