Gene interactions and pathways from curated databases and text-mining

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FGF16 — OTX2

Text-mined interactions from Literome

Liu et al., Development 2001 : However, in the absence of Gbx2, FGF8 can nevertheless repress Otx2 expression in midbrain explants
Miyazaki et al., Dev Genes Evol 2007 : We also showed that all the cells of the animal hemisphere are capable of expressing Hr-Otx in response to the FGF signal
Rössler et al., Neuroscience 2010 : We found that Shh, FGF8 and Wnt1 induced the expression of Lmx1a and Otx2 in nmNSCs resulting in the differentiation of up to 39 % of the nmNSCs into neurons expressing Pitx3