Gene interactions and pathways from curated databases and text-mining

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CALML3 — FAS

Text-mined interactions from Literome

Wesche-Soldato et al., Am J Pathol 2007 (Hepatitis...) : Here, we report that although Fas expression on splenocytes and hepatocytes is up-regulated by CLP and is inhibited by in vivo short interfering RNA, FasL as well as the frequency of CD8 ( + ) T cells are differentially altered by sepsis in the spleen ( no change in FasL, decreased percentage of CD8 ( + ) and CD4 ( + ) T cells ) versus the liver ( increased FasL expression on CD8 ( + ) T cells and increase in percentage/number )
Gao et al., Crit Care Med 2012 (Sepsis) : TLR3 deficiency significantly decreased CLP induced cardiac-myocyte apoptosis and attenuated CLP induced Fas and Fas ligand expression in the myocardium