Gene interactions and pathways from curated databases and text-mining

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CXCL9 — EGFR

Text-mined interactions from Literome

Mascia et al., Am J Pathol 2003 (Dermatitis, Contact...) : Conversely, EGFR signaling blockade produces opposite effects, with increased CCL2, CCL5, and CXCL10, and reduced CXCL8 expression
Ovrevik et al., Eur Respir J 2011 : TACE/TGF-a/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components ... However, EGFR inhibition strongly reduced CXCL8 release induced by all test compounds and selected compounds increased EGFR phosphorylation
Chang et al., PloS one 2013 : Here we show that EGFR activity was markedly decreased during the evolution of resistance to the EGFR tyrosine kinase inhibitor ( TKI ) erlotinib, with a concomitant increase of mitogen-inducible gene 6 (Mig6) , a negative regulator of EGFR through the upregulation of the PI3K-AKT pathway