Gene interactions and pathways from curated databases and text-mining

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APCS — IL10

Text-mined interactions from Literome

Gray et al., Blood 2002 : In the present study we have shown that induction of IL-10 production was due to effects of H-ferritin on adherent antigen presenting cells (APCs) in blood and monocyte derived dendritic cells ( MoDCs ) ... These results are consistent with the thesis that H-ferritin induces B7-H1 and CD86 ( B7-2 ) on APCs , which in turn induce IL-10 production from regulatory T cells
Gregg et al., J Immunol 2005 (Diabetes Mellitus, Type 1) : Insulin beta-chain (INSbeta) 9-23 peptide was expressed on an Ig, and the aggregated ( agg ) form of the resulting Ig-INSbeta triggered IL-10 production by APCs , and expanded IL-10 producing T regulatory cells
Pepys et al., J Immunol Methods 2012 (Amyloidosis) : Importantly, we demonstrate that, contrary to reports using recombinant proteins and less well characterized preparations, neither CRP nor SAP stimulate the release by human peripheral blood mononuclear cells in vitro of any TNFa, IL-6 or IL-8, nor does SAP cause release of IL-1ß or IL-10
Meier et al., Eur J Biochem 1996 : SAPKK-4 was the only SAP kinase-1 activator induced by interleukin-1 or ultraviolet irradiation, while two SAP kinase-1 activators, SAPKK-1 and SAPKK-5, were induced by osmotic shock or anisomycin
Sad et al., J Immunol 1997 : IL-2 synthesis was the most sensitive, as stimulation of IL-4 treated Tc1 cells with higher numbers of APCs partially restored IFN-gamma, TNF, and IL-10 , but not IL-2, synthesis