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CD4 — HRAS
Text-mined interactions from Literome
Popik et al., Mol Cell Biol 1996
:
Surprisingly, the
CD4 mediated signaling, induced by the HIV-1 binding, did not
result in stimulation of the
Ras GTP binding activity or its association with Raf-1, indicating that the signaling pathway generated by the HIV-1 binding is not identical to the classical Ras/Raf-1 pathway
Jabado et al., J Immunol 1997
:
This may result in inefficient signaling, partially accounting for the inhibitory
effects of the
CD4 ligands on both
p21ras and calcium-activation pathways