Gene interactions and pathways from curated databases and text-mining

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CD4 — CD81

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Tseng et al., Cell Immunol 2001 : However, crosslinking of CD81 molecules on TCRgammadelta ( + ) T cells, in the absence of anti-CD3 stimulation, resulted in cytokine production and enhanced IL-2 induced proliferation, demonstrating that physical association with CD4 or CD8 is not necessary for CD81 signaling
Imai et al., J Immunol 1995 (Burkitt Lymphoma) : Finally, we found that the binding of p56lck to CD4 strongly inhibited its association with CD81 and CD82