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MADD — TNFSF10

Text-mined interactions from Literome

Li et al., J Biol Chem 2010 : However, in cells susceptible to TRAIL treatment, TRAIL induces a reduction in MADD phosphorylation levels resulting in MADD dissociation from, and Fas associated death domain association with DR4, which allows death inducing signaling complex ( DISC ) formation leading to apoptosis
Li et al., Thyroid 2013 (Thyroid Neoplasms) : Interestingly, while TRAIL induces a significant reduction in the levels of phospho-Akt ( pAkt ) and phospho-MADD ( pMADD ) in TRAIL-sensitive cells, it fails to do so in TRAIL-resistant cells
Turner et al., PloS one 2013 (Breast Neoplasms) : MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells