Comitato et al., Mol Nutr Food Res 2010
(Breast Neoplasms) :
Moreover, PTRF treatment induces ER-dependent genes expression ( macrophage inhibitory cytokine-1, early growth response-1 and Cathepsin D ) which is inhibited by the ER inhibitor, ICI 182.780, and induces DNA fragmentation
Joshi et al., J Cell Biol 2012
(Breast Neoplasms...) :
pCav1 is therefore a mechanotransducer that acts via PKC to relieve Egr1 transcriptional inhibition of Cav1 and cavin-1 , defining a novel feedback regulatory loop to regulate caveola biogenesis