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PDCD11 — PTGS2
Text-mined interactions from Literome
El-Bikai et al., Arthritis Res Ther 2010
(Osteoarthritis) :
It
inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and
NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release,
COX-2 expression and p38 MAPK phosphorylation
Vaid et al., PloS one 2011
:
Further, GSPs inhibited the activation of
NF-?B/p65 , an upstream
regulator of
COX-2 , in melanoma cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited cell migration
Singh et al., PloS one 2011
(Melanoma...) :
Moreover, EGCG inhibited the activation of
NF-?B/p65 , an upstream
regulator of
COX-2 , in A375 melanoma cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited cell migration
Singh et al., PloS one 2013
(Carcinoma, Non-Small-Cell Lung...) :
Honokiol inhibited PGE2 enhanced migration of NSCLC cells, inhibited the activation of
NF-?B/p65 , an upstream
regulator of
COX-2 , in A549 and H1299 cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-?B, also inhibited migration of NSCLC cells
Sheng et al., Cancer Res 1998
(Colonic Neoplasms...) :
Previously, we have shown that forced expression of
prostaglandin endoperoxide synthase-2 [ also called cyclooxygenase (COX) 2 ]
leads to inhibition of
programmed cell death in intestinal epithelial cells