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JUN — NPY
Text-mined interactions from Literome
Chen et al., Regul Pept 2005
(Hypertrophy) :
After 24-h treatment,
NPY ( 100 nM ) significantly
increased 3H-leucine incorporation and
c-Jun mRNA expression, concomitant with augment of CaN activity and protein level in cardiomyocytes compared to those cells without NPY treatment
Son et al., Exp Neurol 2007
(Constriction, Pathologic...) :
Moreover, transcription factor
c-Jun regulates the expressions of both VIP and
NPY in cultured DRG neurons ... To elucidate the role of c-Jun in the induction of neuropathic pain hypersensitivity, we examined whether activated
c-Jun affects pain behavior and the expressions of VIP and
NPY following chronic constriction injury ( CCI ) of rat sciatic nerve ... These results show that the activation of
c-Jun in DRGs
induces VIP and
NPY upregulation and contributes to the pathogenesis of neuropathic pain following CCI