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NFKB1 — TMSB4X
Text-mined interactions from Literome
Sosne et al., Exp Eye Res 2007
(Keratitis) :
The purpose of this study was to determine the
effect of
thymosin beta 4 (Tbeta4) on
NFkappaB protein levels, activation, phosphorylation, and nuclear translocation in a model of tumor necrosis factor (TNF)-alpha mediated corneal inflammation ... In contrast,
Tbeta4 blocked nuclear translocation of the
NFkappaB p65 subunit in TNF-alpha stimulated corneal epithelial cells ...
Tbeta4 , a protein with diverse cellular functions including wound healing and suppression of inflammation,
inhibits the activation of
NFkappaB in TNF-alpha stimulated cells
Qiu et al., FASEB J 2011
:
Thymosin beta4 inhibits TNF-alpha induced
NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK