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NFKB1 — SNAP25
Text-mined interactions from Literome
Simpson et al., J Neurochem 1999
:
SNAP also
enhanced nuclear protein expression of the p65 subunit of
NF-kappaB
Mendes et al., Inflamm Res 2002
:
SNAP inhibited IL-I induced
NF-kappaB activation and NOS II expression
Aizawa et al., Circ Res 2003
:
The
effects of
SNAP and CNP on
NF-kappaB are mediated by cAMP dependent protein kinase (PKA) but not cGMP dependent protein kinase ( PKG ) based on the findings that the selective PKA inhibitor, PKI, abolished the effects of SNAP and CNP on NF-kappaB, whereas the PKG inhibitor Rp-8-Br-PET-cGMP had no effect
Fass et al., Brain Res 2004
:
SNAP and SNP, but not SIN-1,
activated the transcription factor
NF-kappaB , as indicated by increases in p65 nuclear immunoreactivity
Chang et al., Exp Mol Med 2004
:
SNAP also
blocked cytokine- induced increase in
NF-kappaB activation, iNOS promoter activity, nuclear translocation of cytosolic NF-kappaB p65 subunit, and IkappaBalpha degradation, which correlated with its inhibitory effect on phosphorylation and ubiquitination of IkappaB
Cheng et al., American journal of physiology. Renal physiology 2006
:
Electrophoretic mobility shift assay indicated that
SNAP stimulated
nuclear factor (NF)-kappaB binding activity in cTAL that was also inhibited by the p38 inhibitor