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FGF23 — IHH

Text-mined interactions from Literome

Chen et al., Hum Mol Genet 2001 (Achondroplasia) : Consistent with the in vivo observations, FGF2 inhibited bone growth in culture and induced downregulation of IHH and PTHrP receptor gene expression
Minina et al., Dev Cell 2002 (Hypertrophy) : We furthermore found that FGF and BMP signaling act in an antagonistic relationship regulating chondrocyte proliferation, Ihh expression, and the process of hypertrophic differentiation
Kawai et al., J Biol Chem 2013 (Disease Models, Animal...) : FGF23/sKL suppressed Indian hedgehog (Ihh) expression and administration of Ihh protein partially rescued the suppressive effect of FGF23/sKL on metatarsal growth