◀ Back to ETS2

ANPEP — ETS2

Text-mined interactions from Literome

Petrovic et al., J Biol Chem 2003 : CD13/APN transcription is induced by RAS/MAPK mediated phosphorylation of Ets-2 in activated endothelial cells ... We investigated the possibility that the induction of CD13/APN is mediated by phosphorylation of Ets-2 via RAS/MAPK ... To confirm a role for endogenous Ets-2 in CD13/APN expression, we specifically abrogated Ets-2 mRNA and protein by siRNA knockdown that significantly inhibited CD13/APN transcription
Hedge et al., Mol Cell Biol 1998 : Expression of c-Maf in human immature myeloblastic cells inhibited CD13/APN-driven reporter gene activity ( 85 to 95 % reduction ) and required the binding of both c-Myb and Ets , but not Maf, to the promoter fragment