Gene interactions and pathways from curated databases and text-mining

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EPHB2 — ITGA5

Text-mined interactions from Literome

Wilson et al., Invest Ophthalmol Vis Sci 2003 : Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase
Han et al., Int J Cancer 2005 (Carcinoma, Non-Small-Cell Lung...) : Overall, these findings suggest that COX-2 inhibitors suppress alpha5beta1 integrin expression in NSCLC through effects on integrin alpha5 gene transcription mediated by Erk activation, increased Sp1, decreased AP-1 DNA binding and inactivation of SAPK/JNK signals
Tyagi et al., Mol Cell Biochem 2008 (Cardiovascular Diseases) : In cultured ECs, Fg binding to intercellular adhesion molecule-1 and to alpha(5)beta(1) integrin , caused phosphorylation of ERK
Chen et al., J Biol Chem 2010 (Colorectal Neoplasms) : rHSP90alpha induced the activities of ERK , PI3K/Akt, and NF-kappaB p65, but only NF-kappaB activation was involved in HSP90alpha induced integrin alpha(V) expression