◀ Back to EPHB2
EPHB2 — ITGA5
Text-mined interactions from Literome
Wilson et al., Invest Ophthalmol Vis Sci 2003
:
Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and
ERK activation through
alpha5beta1 integrin and PI 3-kinase
Han et al., Int J Cancer 2005
(Carcinoma, Non-Small-Cell Lung...) :
Overall, these findings suggest that COX-2 inhibitors suppress alpha5beta1 integrin expression in NSCLC through effects on
integrin alpha5 gene transcription
mediated by
Erk activation, increased Sp1, decreased AP-1 DNA binding and inactivation of SAPK/JNK signals
Tyagi et al., Mol Cell Biochem 2008
(Cardiovascular Diseases) :
In cultured ECs, Fg binding to intercellular adhesion molecule-1 and to
alpha(5)beta(1) integrin ,
caused phosphorylation of
ERK
Chen et al., J Biol Chem 2010
(Colorectal Neoplasms) :
rHSP90alpha induced the activities of
ERK , PI3K/Akt, and NF-kappaB p65, but only NF-kappaB activation was
involved in HSP90alpha induced
integrin alpha(V) expression