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EPHB2 — GATA6
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Fowkes et al., Biol Reprod 2002
:
Electrophoretic mobility shift assays for SF-1 and GATA revealed that PMA failed to affect SF-1 binding but enhanced GATA binding to a consensus GATA oligonucleotide, an effect that was blocked with U0126 pretreatment, suggesting that
GATA may
mediate ERK activation of alphaGSU transcription
Adachi et al., Oncogene 2008
:
Oncogenic Ras upregulates NADPH oxidase 1 gene expression through
MEK-ERK dependent phosphorylation of
GATA-6 ... On the basis of these results, we propose that oncogenic Ras signaling upregulates the transcription of Nox1 through
MEK-ERK dependent phosphorylation of
GATA-6