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CCL2 — MMP2
Text-mined interactions from Literome
Werle et al., Cardiovasc Res 2002
:
MCP-1 also
induced secretion of
matrix metalloproteinase (MMP)-2 which along with ERK activation was inhibited by PD098059
Wang et al., PloS one 2011
(Inflammation) :
Furthermore, exposure of young VSMC to TGF-ß1 increases levels of
MCP-1 , and
MMP-2 activation , to levels of untreated VSMC from old rats
Park et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2011
:
MMP inhibitors, such as doxycycline, minocycline, and batimastat, significantly
reduced the cerebral infarct size, and the expressions of
monocyte chemotactic protein-1 (MCP-1) , tumor necrosis factor-a (TNF-a), and indoleamine 2,3-dioxygenase (IDO)
Li et al., Fertil Steril 2012
(Endometriosis) :
The
CCL2 can
increase the expression of proliferating cell nuclear antigen, survivin, and
matrix metalloproteinase 2 , and decrease the expression of tissue inhibitor of metalloproteinase 1 and 2, and promote the viability, proliferation and invasiveness of ESCs by activating Akt and MAPK/Erk1/2 signal pathway, but not p38 and JNK signal pathway