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CALM3 — CCL2
Text-mined interactions from Literome
Zeng et al., Acta Pharmacol Sin 2005
:
Inhibitors of PKC ( calphostin C, 50-500 nmol/L and RO-31-8220, 10-100 nmol/L ),
CaM ( W7, 28-280 micromol/L ), ERK1/2 MAPK ( PD 98059, 2-20 micromol/L ), p38 MAPK ( SB 203580, 0.6-6 micromol/L ), JNK MAPK ( curcumin, 2-10 micromol/L ), and NF-kappaB ( PDTC, 10-100 nmol/L ) markedly reduced Hcy 100 micromol/L induced production of MCP-1 and IL-8 in human cultured whole blood, but the inhibitors of PTK ( genistein, 2.6-26 micromol/L and tyrphostin, 0.5-5 micromol/L )
had no obvious effect on
MCP-1 and IL-8 production
Yamazaki et al., J Infect Chemother 2012
:
CAM inhibited the release of chemotactic activity and the production of interleukin (IL)-8 and macrophage chemotactic protein
(MCP)-1
Shen et al., J Nutr 2013
(Inflammation...) :
U73122 attenuated 18 : 2t10, c12 mediated insulin resistance within 48 h and suppression of the mRNA levels of peroxisome proliferator activated receptor ( PPAR ) ?, insulin stimulated glucose transporter-4, acetyl-CoA carboxylase-1, and stearoyl-CoA desaturase-1, and the protein levels of PPAR? within 18-24 h. U73122 inhibited 18 : 2t10, c12 mediated induction of the inflammatory related genes
calcium/calmodulin dependent protein kinase-ß, cyclooxygenase-2,
monocyte chemoattractant protein-1 , interleukin (IL)-6, and IL-8, secretion of IL-6 and IL-8, and the activation of extracellular signal related kinase, c-Jun N-terminal kinase, and c-Jun within 18-24 h