Gene interactions and pathways from curated databases and text-mining

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C1QA — CCL2

Text-mined interactions from Literome

Groeneveld et al., J Immunol 2005 : Decorin and biglycan strongly inhibited C1q binding to human endothelial cells and U937 cells, and biglycan suppressed C1q induced MCP-1 and IL-8 production by human endothelial cells
Fraser et al., J Neurochem 2010 (Blister) : Microglia added to C1q coated wells or fed apoptotic neurons or neuronal blebs coated with C1q suppressed the lipopolysaccharide induced production of proinflammatory cytokines interleukin (IL)-1alpha, IL-1beta, IL-6 and TNF-alpha, while the presence of C1q enhanced levels of the chemokine MCP-1/CCL2
Verardi et al., J Periodontal Res 2011 (Peri-Implantitis...) : The C1q interactions with peri-implantitis and healthy fibroblasts increased secretion of the chemokines interleukin-6 and interleukin-8 twofold, and monocyte chemoattractant protein-1 fourfold over baseline values, whereas periodontitis fibroblasts were unresponsive