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BCL6 — IFNG
Text-mined interactions from Literome
Huang et al., J Invest Dermatol 2001
(Acute Disease...) :
Interleukin-13 and interleukin-4 were unable to block
interferon-gamma mediated induction of STAT1 or
BCL-6 , however, or the upregulation of intercellular adhesion molecule 1 and HLA-DR ... The ability of
interferon-gamma to
induce the transcription repressor
BCL-6 may also contribute to the overall immunologic events in skin, including suppression of the intermediates in the synthetic pathway leading to expression of the T cell costimulatory ganglioside CDw60
Zhou et al., Exp Mol Pathol 2005
:
In this study, we report that
BCL-6 expression is
induced by
IFN-gamma in Jurkat cells and in nontransformed T cells polarized toward the Th1 phenotype
Yu et al., Immunity 2009
:
Bcl-6 bound to the promoters of the Th1 and Th17 cell transcriptional regulators T-bet and RORgammat and
repressed IFN-gamma and IL-17 production