Gene interactions and pathways from curated databases and text-mining

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BCL6 — IFNG

Text-mined interactions from Literome

Huang et al., J Invest Dermatol 2001 (Acute Disease...) : Interleukin-13 and interleukin-4 were unable to block interferon-gamma mediated induction of STAT1 or BCL-6 , however, or the upregulation of intercellular adhesion molecule 1 and HLA-DR ... The ability of interferon-gamma to induce the transcription repressor BCL-6 may also contribute to the overall immunologic events in skin, including suppression of the intermediates in the synthetic pathway leading to expression of the T cell costimulatory ganglioside CDw60
Zhou et al., Exp Mol Pathol 2005 : In this study, we report that BCL-6 expression is induced by IFN-gamma in Jurkat cells and in nontransformed T cells polarized toward the Th1 phenotype
Yu et al., Immunity 2009 : Bcl-6 bound to the promoters of the Th1 and Th17 cell transcriptional regulators T-bet and RORgammat and repressed IFN-gamma and IL-17 production