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HSPB3 — WNT3
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Zi et al., Cancer Res 2005
(Neoplasm Invasiveness...) :
The ability of Frzb/secreted Frizzled related
protein 3 ( sFRP3 ) to
inhibit Wnt signaling and the localization of Frzb/sFRP3 on chromosome 2q to a region frequently deleted in cancers have led some investigators to hypothesize that Frzb/sFRP3 is a tumor suppressor gene
Jang et al., Cell stem cell 2013
:
Here, we report that neuronal activity decreases the expression of secreted frizzled related
protein 3 ( sFRP3 ), a naturally secreted
Wnt inhibitor highly expressed by adult dentate gyrus granule neurons
Repudi et al., J Cell Sci 2013
:
WISP3 (
Wnt induced secreted
protein 3 ) is a multi-domain protein of mesenchymal origin