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IL4 — TP63
Text-mined interactions from Literome
KaliĆski et al., J Immunol 2000
:
However, in contrast to IFN-gamma,
IL-4 inhibits the CD40 ligand induced production of inactive
IL-12p40 and the production of either form of IL-12 induced by LPS, which may explain the view of IL-4 as an IL-12 inhibitor
Becker et al., J Immunol 2001
:
Finally, we observed that
IL-4 mediated repression of IL-12
p40 promoter activity is critically dependent on an intact GA-12 sequence
Kelsall et al., Ann N Y Acad Sci 1996
(Colitis) :
Finally, we show that IL-10 has a potent capacity to shut down CD40 induced IL-12 p40 secretion ; and, in addition,
IL-4 partially
inhibits CD40 induced IL-12
p40 secretion and enhances IL-10 mediated inhibition in an additive fashion