Gene interactions and pathways from curated databases and text-mining

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IL4 — TP63

Text-mined interactions from Literome

KaliƄski et al., J Immunol 2000 : However, in contrast to IFN-gamma, IL-4 inhibits the CD40 ligand induced production of inactive IL-12p40 and the production of either form of IL-12 induced by LPS, which may explain the view of IL-4 as an IL-12 inhibitor
Becker et al., J Immunol 2001 : Finally, we observed that IL-4 mediated repression of IL-12 p40 promoter activity is critically dependent on an intact GA-12 sequence
Kelsall et al., Ann N Y Acad Sci 1996 (Colitis) : Finally, we show that IL-10 has a potent capacity to shut down CD40 induced IL-12 p40 secretion ; and, in addition, IL-4 partially inhibits CD40 induced IL-12 p40 secretion and enhances IL-10 mediated inhibition in an additive fashion