Gene interactions and pathways from curated databases and text-mining

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SOCS3 — TYR

Text-mined interactions from Literome

Mahboubi et al., J Biol Chem 2003 : Desensitization of signaling by oncostatin M in human vascular cells involves cytoplasmic Tyr residue 759 in gp130 but is not mediated by either Src homology 2 domain containing tyrosine phosphatase 2 or suppressor of cytokine signaling 3
Haan et al., J Biol Chem 2003 : Jak mediated phosphorylation of SOCS3 decreased SOCS3 protein half-life, and phosphorylation of both Tyr204 and Tyr221 was required to fully destabilize SOCS3
Zhang et al., Zhonghua Bing Li Xue Za Zhi 2012 (Adenocarcinoma...) : The effects of SOCS3 on Pyk2 expression, Pyk2 Tyr 402 and ERK1/2 phosphorylations were assessed by Western blot