Gene interactions and pathways from curated databases and text-mining

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LGALS1 — MAPK3

Text-mined interactions from Literome

Hsieh et al., Oncogene 2008 (Carcinoma, Squamous Cell...) : The binding of Gal-1 to NRP1 enhanced VEGFR-2 phosphorylation and stimulated the activation of the mitogen activated protein ( MAP ) kinases SAPK1/JNK ( stress activated protein kinase-1/c-Jun NH2-terminal kinase )
Shimizu et al., Lab Invest 2009 (Disease Models, Animal...) : Moreover, recombinant Gal-1 induced tyrosine phosphorylation of the cytoplasmic domain of nephrin and activation of the extracellular signal regulated kinase 1/2 in podocytes
Roda et al., Gastroenterology 2009 (Adenocarcinoma...) : Down-regulation of Gal-1 by small interference RNA was used to analyze the involvement of Gal-1/tPA interaction in extracellular signal regulated kinase 1/2 activation, cell proliferation, and invasion in pancreatic and fibroblastic cells
Brandt et al., Cell death & disease 2010 : In this study we first show that gal-1 initiates the activation of c-Jun N-terminal kinase (JNK), mitogen activated protein kinase kinase 4 ( MKK4 ), and MKK7 as upstream JNK activators in Jurkat T cells