Yu et al., Horm Metab Res 2010
(Hyperglycemia...) :
The expression of a constitutively active form of p38-MAPK in the cells inhibited the ABCA1 promoter activity, irrespective of the presence of glucose
Mulay et al., PloS one 2013
(MAP Kinase Signaling System) :
We demonstrate that in Chinese Hamster Ovary ( CHO ) cells and human hepatic HuH7 cells, extracellular signal regulated kinase 1/2 ( Erk1/2 ) inhibition reduces PPARa-inducible ABCA1 protein levels, while ectopic expression of constitutively active H-Ras, K-Ras and MAPK/Erk kinase 1 (Mek1) increases ABCA1 protein expression, respectively