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IL22 — S100A7
Text-mined interactions from Literome
Liang et al., J Exp Med 2006
:
IL-22 in conjunction with IL-17A or IL-17F synergistically induced the expression of beta-defensin 2 and S100A9 and additively
enhanced the expression of
S100A7 and S100A8
Gläser et al., J Invest Dermatol 2009
(Dermatitis, Atopic) :
Surprisingly, tumor necrosis factor-alpha enhanced psoriasin release in primary keratinocytes was inhibited by the Th2-cytokines IL-4 and -13, whereas
IL-17 and -22 induced
psoriasin
Pennino et al., J Allergy Clin Immunol 2013
(Asthma...) :
On the one hand, IFN-? antagonized
IL-22 mediated induction of the antimicrobial peptide
S100A7 and epithelial cell migration in bronchial epithelial cells
Datta Mitra et al., J Invest Dermatol 2013
(Psoriasis) :
Interestingly, BE inhibited the
IL-22 induced gene expression of AKT1, MTOR, chemokines [ IL-8 and RANTES ( regulated upon activation, normal T-cell expressed and secreted ) ], and
psoriasin ( S100A7 ) more significantly than Vit-D