Schmidt et al., Otol Neurotol 2002
(Cholesteatoma, Middle Ear) :
It has been shown that BMP-2 expression is inducible by interleukin 1 in synovial fibroblasts and that BMP-2 in combination with interleukin 1alpha is able to stimulate the formation of osteoclast-like multinucleated cells in co-cultures of osteoblast-like cells and hematopoietic cells
Yoshioka et al., Eur J Immunol 2012
:
Dorsomorphin efficiently suppressed IL-2 production even at low doses in mouse CD4 ( + ) T cells, suggesting that the BMP-Smad signalling physiologically regulates IL-2 transcription in these cells ... In addition, recombinant BMP2 induced a dose dependent multiphasic pattern of IL-2 production, while Noggin suppressed IL-2 production at higher doses in Jurkat cells
Fowler et al., Biochem Biophys Res Commun 1998
(Osteoarthritis) :
Induction of bone morphogenetic protein-2 by interleukin-1 in human fibroblasts ... Utilizing a specific antibody, levels of bone morphogenetic protein-2 protein in conditioned medium from synovial fibroblasts were also up-regulated in the presence of interleukin-1