Gene interactions and pathways from curated databases and text-mining

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F2RL1 — ICAM1

Text-mined interactions from Literome

Seeliger et al., FASEB J 2003 (Dermatitis...) : PAR-2 mediated up-regulation of E-selectin and cell adhesion molecule ICAM-1 ; enhanced plasma extravasation was observed in humans and mice and of interleukin-6 in mice in vivo
Buddenkotte et al., J Invest Dermatol 2005 (Dermatitis, Atopic) : Use of NF-kappaB inhibitors prevented upregulation of the cell adhesion molecule ICAM-1 in KTC indicating a direct role of NF-kappaB in PAR2 mediated upregulation of ICAM-1
Shimada et al., Oral Microbiol Immunol 2009 : A. actinomycetemcomitans extract induced IL-8 and ICAM-1 expression in gingival epithelial cells is mediated by PAR-2