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HGF — MMP27

Text-mined interactions from Literome

Hamasuna et al., Int J Cancer 1999 (Brain Neoplasms...) : MT1 -MMP , a cell-surface activator of proMMP-2, was also up-regulated by HGF/SF in a dose dependent manner
Hanzawa et al., Carcinogenesis 2000 (Carcinoma, Squamous Cell...) : Here we examined the effect of HGF on E1AF and MMP gene expression in terms of the invasive potential of the oral squamous cell carcinoma cell line HSC3
Wang et al., Biochem Biophys Res Commun 2000 (MAP Kinase Signaling System) : Hepatocyte growth factor enhances MMP activity in human endothelial cells
Imafuku et al., Clin Chim Acta 2002 : We also found a definite effects on copper, angiotensin converting enzyme (ACE), matrix metalloproteinase (MMP)-1 , -3 and -9, tissue inhibitor of matrix metalloproteinase ( TIMP ) -1, hepatocyte growth factor (HGF) , monoamine oxidase ( MAO ), vitamin B ( 12 ), ACTH and IL-6, though the mechanisms were not clear
Hirata et al., Biol Reprod 2003 : Membrane type-1 MMP mRNA expression in the stromal cells was augmented by tumor necrosis factor alpha (TNFalpha), IL-6, HGF , and 12-O-tetradecanoylphorbol 13-acetate
Fujiuchi et al., Oncol Rep 2003 (Neoplasm Invasiveness...) : Furthermore, HGF also increased the production of MMP-1 and -9, MT1-MMP , u-PA and uPAR of these cells
Li et al., World J Gastroenterol 2005 (Colorectal Neoplasms...) : Compared with controls, MMP-2 and MMP-9 mRNA expressions were up-regulated by HGF ( 0.997+/-0.011 vs 1.207+/-0.003, t = 35.002,P = 0.001 < 0.01 ; 0.387+/-0.128 vs 0.971+/-0.147, t = 106.036, P = 0.0000 < 0.01, respectively ) ; compared with controls, TIMP-1, TIMP-2 mRNA expressions were increased by PD98059 ( 1.344+/-0.007 vs 1.905+/-0.049, t = 17.541, P = 0.003 < 0.01 ; 1.286+/-0.020 vs 1.887+/-0.022,t = 24.623, P = 0.002 < 0.01, respectively )
Ide et al., Int J Cancer 2006 (Neoplasm Invasiveness...) : Conversely, the elevated cancer invasion, MMP activity and c-Met phosphorylation of PK8 cells were reduced by the removal of HGF from hypoxic conditioned medium
Aparicio et al., C R Seances Soc Biol Fil 1998 (Colonic Neoplasms...) : After 24 or 48 h of culture in medium supplemented with HGF, transforming growth factor-alpha ( TGF-alpha ) or sodium butyrate, MMP production by DHD/K12 cells was stimulated by HGF and TGF-alpha and inhibited by sodium butyrate