Gene interactions and pathways from curated databases and text-mining

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CASP3 — PNPLA2

Text-mined interactions from Literome

Lauber et al., Cell 2003 (Inflammation) : Further analysis showed that lysophosphatidylcholine was released from apoptotic cells due to the caspase-3 mediated activation of the calcium independent phospholipase A(2)
Zhao et al., J Biol Chem 2006 (Ovarian Neoplasms) : Caspase-3 dependent activation of calcium independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells
Tan et al., Biochem Biophys Res Commun 2010 (Bone Neoplasms...) : In this report, pigment epithelium derived factor (PEDF) induced apoptosis in the chondrosarcoma cell line - JJ012, with upregulation of Bax, Fas, caspase-3 and -6 and downregulation of Bcl-2