Gene interactions and pathways from curated databases and text-mining

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AHSA1 — MAP3K4

Text-mined interactions from Literome

Abell et al., Mol Cell Biol 2005 (MAP Kinase Signaling System...) : Together, these data demonstrate MEKK4 regulation of p38 and that substrates downstream of p38 control cellular homeostasis ... The findings are the first demonstration that MEKK4 regulated p38 activity is critical for neurulation
Keil et al., Cell Death Differ 2013 : Thus, we show for the first time that Atg5 activity is controlled by phosphorylation and, moreover, that the spatial regulation of p38 by Gadd45ß/MEKK4 negatively regulates the autophagic process
Warr et al., Dev Cell 2012 (Gonadal Dysgenesis, 46,XY...) : Taken together, our data suggest a requirement for GADD45? in promoting MAP3K4 mediated activation of p38 MAPK signaling in embryonic gonadal somatic cells for testis determination in the mouse