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CDKN1A — PLD5
Text-mined interactions from Literome
Kwun et al., FEBS Lett 2003
:
Transcriptional
repression of cyclin dependent kinase inhibitor
p21 gene by
phospholipase D1 and D2
Kuribara et al., J Biol Chem 1995
:
Synergistic
activation of rat brain
phospholipase D by ADP-ribosylation factor and rhoA
p21 , and its inhibition by Clostridium botulinum C3 exoenzyme ... Interestingly, recombinant isoprenylated rhoA
p21 and ARF synergistically
activated rat brain
PLD ; a similar pattern was seen with the partially purified PLD activating factor ... These findings suggest that rhoA
p21 regulates rat brain
PLD in concert with ARF, and that isoprenylation of rhoA p21 is essential for PLD regulation in vitro
Carnero et al., Mol Cell Biol 1995
(Second Messenger Systems) :
After microinjection,
ras-p21 induces a rapid
PLD activation followed by a late PLA2 activation