Gene interactions and pathways from curated databases and text-mining

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ALX1 — IL2

Text-mined interactions from Literome

Greene et al., J Biol Chem 2003 : ALX overexpression in Jurkat T cells results in inhibition of IL-2 promoter activation after stimulation with superantigen
Shapiro et al., J Biol Chem 2004 : Overexpression of ALX inhibits the transcriptional activation of the interleukin 2 promoter during T cell activation, specifically affecting CD28 mediated activation of the RE/AP element of the interleukin 2 promoter
Shapiro et al., J Biol Chem 2005 : The adaptor protein ALX acts downstream of CD28 to regulate the interleukin-2 (IL-2) promoter during T cell activation