Gene interactions and pathways from curated databases and text-mining

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MOG — TNF

Text-mined interactions from Literome

Lobell et al., J Immunol 2003 (Encephalomyelitis, Autoimmune, Experimental) : We failed to detect any effects on ex vivo MOG-peptide induced IFN-gamma, TNF-alpha , IL-6, IL-4, IL-10, and brain derived neurotropic factor expression in splenocytes or CNS derived lymphocytes
Jana et al., Free Radic Biol Med 2005 (Encephalomyelitis, Autoimmune, Experimental...) : Interestingly, both IL-1beta and TNF-alpha markedly inhibited the expression of MOG , CNPase, and PLP but not MBP, the effect that was blocked by antioxidants such as N-acetylcysteine (NAC) and pyrrolidine dithiocarbamate ( PDTC )
Matsuki et al., Int Immunol 2006 (Encephalomyelitis, Autoimmune, Experimental) : We found that both IFN-gamma and IL-17 production and proliferation were reduced in IL-1-/- T cells upon stimulation with MOG , while IFN-gamma, IL-17 and tumor necrosis factor-alpha production and proliferation were enhanced in IL-1Ra-/- T cells