Gene interactions and pathways from curated databases and text-mining

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CEACAM5 — TNF

Text-mined interactions from Literome

Grünberg et al., Tumour Biol 2000 (Breast Neoplasms) : Furthermore, CEA , ICAM-1 and CD44v6 were increased by TNF-alpha plus calcitriol
Filella et al., Tumour Biol 2001 : In contrast, CEA significantly increased the production of IL-6 ( p < 0.001 ) and TNF-alpha ( p = 0.002 ), while PSA significantly decreased IL-1beta ( p < 0.001 ), IL-6 ( p = 0.031 ) and TNF-alpha ( p < 0.0001 ) production
Dukic-Stefanovic et al., J Neurochem 2003 : Chicken egg albumin-AGE (CEA-AGE) , used as model AGE, induces nitric oxide ( NO ), TNF-alpha and IL-6 production
Majuri et al., APMIS 1994 (Adenocarcinoma...) : The expression of CEA on cultured endothelial cells can be enhanced by TNF-alpha or IFN-gamma, and decreased by IL-4
Takahashi et al., Cancer Res 1993 (Colonic Neoplasms) : Maximal induction of CEA by IFN-gamma and tumor necrosis factor alpha (TNF-alpha) in the colon carcinoma cell line HT-29 occurs at 5-6 days with maximal secreted levels at 14 ng/ml for IFN-gamma and 20 ng/ml for TNF-alpha
Gangopadhyay et al., Cancer Lett 1997 (Colorectal Neoplasms...) : Results demonstrate that CEA induced IL-1alpha and TNF-alpha production involves tyrosine phosphorylation and the signaling in CEA treated cells is different than that seen with LPS stimulation