Gene interactions and pathways from curated databases and text-mining

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CD83 — TNF

Text-mined interactions from Literome

Sato et al., J Immunol 1999 : TNF-alpha induced the cluster formation of the cells and the enhancement of cell surface expression levels of CD83 , CD86, and HLA-DR, and T cell stimulatory capacity, whereas the capacities for the endocytosis and the chemotactic migration were suppressed in these cells
Kim et al., Int Immunopharmacol 2004 : Phosphatidic acid and tumor necrosis factor-alpha induce the expression of CD83 through mitogen activated protein kinase pathway in a CD34+ hematopoietic progenitor cell line, KG1 ... In the presence of tumor necrosis factor (TNF)-alpha , PA but not lyso-PA up-regulated CD83 on KG1 cells ... However, the up-regulation of CD83 by PA/TNF-alpha on KG1 was significantly abrogated by PD98059, a specific inhibitor of ERK kinase, but was enhanced by SP600125, a JNK inhibitor ... Bis-indolylmaleimide, an inhibitor of protein kinase C, partially blocked the up-regulation of CD83 and ERK phosphorylation induced by PA and TNF-alpha ... These results suggest that PA and TNF-alpha induce the up-regulation of CD83 and that their action is regulated by ERK and JNK
Reich et al., Exp Dermatol 2004 (Dermatitis, Atopic...) : Stimulation of day 8 DCs from AD patients with TNF-alpha and IL-1beta enhanced the expression of CD83 and CD86 and restored the production of IL-16
Dudziak et al., J Immunol 2005 : Stimulation of PBMCs with PHA, TNF-alpha , or LPS leads to the up-regulation of the full-length CD83 transcript and to a strong down-regulation of two of the three smaller transcripts
Tang et al., J Zhejiang Univ Sci B 2005 : TNFalpha treatment induced DCs maturation and up-regulation of CD80, CD86 and CD83
Oudijk et al., Mol Immunol 2008 : Functional antagonism by GM-CSF on TNF-alpha induced CD83 expression in human neutrophils ... TNFalpha induced expression of CD83 in leukocytes is mediated by NF-kappab ... The aim of our present study was to investigate the underlying mechanism of a unique functional antagonism between GM-CSF and TNFalpha induced up-regulation of CD83 in human neutrophils
Wu et al., J Lipid Res 2012 (Hyperlipidemias) : Abundance of miR-181a attenuated ox-LDL induced CD83 and CD40 expression, inhibited the secretion of interleukin (IL)-6 and TNF-a , and up-regulated IL-10, an important anti-inflammatory cytokine that was inhibited by ox-LDL
Xue et al., Int Immunopharmacol 2013 : We elucidated that IFN-? up-regulated the expression of MHC II, CD40, CD80, CD83 and CD86 molecules on BMDCs, down-regulated the activity of pinocytosis and phagocytosis by BMDCs, and induced higher levels of IL-12 and TNF-a secreted by BMDCs
Vuckovic et al., Exp Hematol 1998 : Additional TNF-alpha treatment induced prominent dendritic processes and surface expression of CD83 on CMRF-44+ DCs