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PRKAB1 — STIM1
Text-mined interactions from Literome
Lang et al., Cell Calcium 2012
(Calcium Signaling) :
The regulation by SGK1 links SOCE to the signaling of a wide variety of hormones and growth factors, the
AMPK dependent regulation of Orai1 and
STIM1 may serve to limit inadequate activation of SOCE following energy depletion, which is otherwise expected to activate SOCE by depletion of intracellular Ca2+ stores due to impairment of the ATP consuming sarco/endoplasmatic reticulum Ca2+ ATPase SERCA
Sundivakkam et al., J Biol Chem 2013
:
Activation of
AMPK using 5-aminoimidazole-4-carboxamide-1-ß-d-ribofuranoside ( AICAR )
resulted in
STIM1 phosphorylation on serine residues and prevented protease activated receptor-1 (PAR-1) induced Ca ( 2+ ) entry