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Diraison et al., Biochem J 2004
:
Real-time PCR ( TaqMan ) analysis showed that SREBP1c up-regulated the expression of FAS ( fatty acid synthase ; 6-fold ), acetyl-CoA carboxylase-1 ( 2-fold ), as well as peroxisomal-proliferator activated receptor-gamma ( 7-fold ), uncoupling protein-2 ( 1.4-fold ) and Bcl2 ( B-cell lymphocytic-leukaemia proto-oncogene 2 ; 1.3-fold )
Felder et al., Biochim Biophys Acta 2005
:
SREBP-1ac did not transactivate the human LDLR and UCP2 promoters but robustly attenuated the transactivation capacity of SREBP-1a, -1c and -2 in cotransfection experiments
Oberkofler et al., J Mol Med (Berl) 2009
(Insulinoma) :
PGC-1beta as well as SREBP-1c and -2 increased transcription from the UCP2 promoter in INS-1E cells