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CITED2 — MMP13

Text-mined interactions from Literome

Yokota et al., J Biol Chem 2003 : CITED2 mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear ... Using the immortalized human chondrocyte cell line, C-28/I2, we investigated whether CITED2 could be responsive to mechanical stimuli, and if so, whether CITED2 could mediate shear-driven regulation of matrix metalloproteinase ( MMP ) genes ... These results indicate that CITED2 plays a major role in shear induced down-regulation of MMP-1 and MMP-13 via a transforming growth factor-beta dependent pathway
Bai et al., FEBS Lett 2007 (Colonic Neoplasms...) : Gene expression profiling revealed that CITED2 knockdown induced matrix metalloproteinase-13 (MMP-13) gene expression in colon cancer cells