Gene interactions and pathways from curated databases and text-mining

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GNAQ — MAPK1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MAPK1 → GNAQ (increases, MAPK1 Activity) Zeng et al., J Biol Chem 2003*
    Evidence: Our results further indicate that Gq/11 proteins specifically mediate KDR signaling such as intracellular Ca2+ mobilization rather than Flt-1-induced CDC42 activation and that a Gq/11 antisense oligonucleotide completely inhibits MAPK phosphorylation induced by KDR but has no effect on Flt-1-induced MAPK activation.