Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Tao et al., J Invest Dermatol 2008 (Melanoma...) : Therefore, TAP expression restores both antigen presentation and immunogenicity in A375 melanoma cells and concomitantly increases IL-12 and IFN-gamma production in tumor antigen-specific CTLs ; TAP should be considered as a part of the immunotherapies for MM
Dumont et al., Immunology 1988 : The T-cell activating protein (TAP) is up-regulated by endogenous IFN-gamma in activated T cells ... Recently, we found that TAP is also augmented by exogenous interferon-gamma (IFN-gamma) in resting T cells ... Endogenously produced IFN-gamma , rather than cell activation per se, is thus responsible for the augmentation of TAP expression in stimulated T cells
Heike et al., Int J Cancer 1996 (Colonic Neoplasms...) : IFN-gamma enhanced the expression of TAP , LMP and HLA-class-I proteins in MZ-MES-1 cells