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IFNG — TGFB3
Text-mined interactions from Literome
Qadir et al., Am J Physiol Gastrointest Liver Physiol 2001
(Granuloma, Foreign-Body...) :
Interleukin-10 (IL-10) and
transforming growth factor-beta ( TGF-beta )
regulate CD4+ T cell
interferon-gamma (IFN-gamma) secretion in schistosome granulomas
Riemekasten et al., Arthritis Rheum 2003
:
Interferon-gamma (IFNgamma), interleukin-2 (IL-2), IL-4,
transforming growth factor beta , and IL-10 production
increased in response to the peptide in young mice ; only
IFNgamma and IL-2 were increased in older, diseased mice
Kuga et al., Oncogene 2003
(Neoplasm Invasiveness...) :
Interferon-gamma suppresses
transforming growth factor-beta induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model
Wen et al., Am J Respir Cell Mol Biol 2004
:
Interferon-gamma inhibits
transforming growth factor-beta production in human airway epithelial cells by targeting Smads ... Because interferon (IFN)-gamma may attenuate pulmonary fibrosis, we hypothesized that
IFN-gamma may
regulate transforming growth factor ( TGF ) -beta production by airway epithelial cells
Qi et al., Infect Immun 2004
(Leishmaniasis, Cutaneous) :
The replication promoting effect of
IFN-gamma on amastigotes was independent of the source and genetic background of Mphis, was apparently not affected by surface opsonization of amastigotes, was not
mediated by interleukin-10 or
transforming growth factor beta , and was observed at different temperatures
Langhorne et al., Immunol Rev 2004
(Inflammation...) :
IFN-gamma and TNF-alpha play a role in both protective immunity and the pathology of the infection, and the inflammatory disease may be
regulated by IL-10 and
transforming growth factor-beta
Sashinami et al., Cytokine 2006
(Salmonella Infections, Animal) :
Treatment of monoclonal antibodies against cytokines showed that
IFN-gamma and interleukin 10 (IL-10) were involved in maintenance of growth of S. Typhimurium mutant on day 10 after infection, and IFN-gamma, TNF-alpha and
transforming growth factor-beta ( TGF-beta ) were
involved in maintenance of growth of this bacterium on day 30 after infection
Young et al., Immunity 2006
:
Although
transforming growth factor-beta ( TGF-beta )
inhibition of
interferon-gamma (IFN-gamma) expression has been known for some time, in this issue of Immunity, the crosstalk between proinflammatory cytokine and TGF-beta signaling that regulates IFN-gamma expression is detailed for the first time
Yu et al., Immunity 2006
(Inflammation) :
NK cells provide the antiinflammatory cytokine
transforming growth factor ( TGF ) -beta , an autocrine/negative
regulator of
IFN-gamma
Burkart et al., Biochem Biophys Res Commun 2008
(Diabetes Mellitus, Type 1) :
Hyperthermia induced Hsp70 expression was decreased by the T-helper 1-associated cytokine
interferon-gamma and
increased by the T-helper 2-associated
transforming growth factor-beta
Sela et al., Immunology 2009
(Lupus Erythematosus, Systemic) :
Upregulation of
transforming growth factor-beta ( TGF-beta ) secretion by T cells, following treatment with hCDR1,
resulted in downregulation of
IFN-gamma production and contributed to the phenotypic changes and magnitude of IL-12 secretion by DCs
Lankat-Buttgereit et al., J Dermatol Sci 1991
:
Interferon-gamma reduces all mRNA steady state levels dose dependently in comparison to the control, while
transforming growth factor-beta simultaneously induces BM-40, alpha 1 and alpha 2 ( IV ) collagen mRNAs
Fitzner et al., Pancreatology 2009
(Autoimmune Diseases...) :
IFN-gamma also caused pancreatic accumulation of CD4-, CD8-, C11b- and CD138 positive cells, and
enhanced pancreatic mRNA expression of interleukin (IL)-1 beta,
transforming growth factor-beta and IFN-gamma itself
Barnum et al., J Immunol 1994
(Inflammation) :
In this report, we show that
transforming growth factor-beta ( TGF-beta ) can significantly
inhibit the capacity of
IFN-gamma , IL-1 beta, and TNF-alpha to augment expression of the central component of complement C3 in the human astroglioma cell line D54-MG. Treatment of D54-MG cells with TGF-beta alone had no dose- or time dependent effect on basal C3 protein or mRNA levels
Spittler et al., Immunology 1997
:
Both constitutive and
interferon-gamma (IFN-gamma) , interleukin-4 (IL-4), IL-6 and tumour necrosis factor-alpha (TNF-alpha) induced human leucocyte antigen ( HLA ) -DR, HLA-DP and HLA-DQ Ag expression on monocytes was significantly
down-regulated by calcitriol, IL-10 and
transforming growth factor-beta ( TGF-beta )
Naganuma et al., Neurol Med Chir (Tokyo) 1996
(Brain Neoplasms...) :
The
effect of
transforming growth factor-beta ( TGF-beta ) secreted by glioblastoma ( T98G ) cells on the secretion of
interferon-gamma (IFN-gamma) by lymphokine activated killer ( LAK ) cells stimulated with tumor cells was investigated in cocultures of LAK and Daudi cells supplemented with T98G culture supernatant, T98G culture supernatant preincubated with anti-TGF-beta 1 and anti-TGF-beta 2 neutralizing antibodies, anti-TGF-beta 1 and anti-TGF-beta 2 antibodies, or natural human TGF-beta 1 or recombinant human TGF-beta 2