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IFNG — NOD2
Text-mined interactions from Literome
Rosenstiel et al., Gastroenterology 2003
:
TNF-alpha and
IFN-gamma regulate the expression of the NOD2 (
CARD15 ) gene in human intestinal epithelial cells
Tötemeyer et al., J Immunol 2006
:
IFN-gamma increases
NOD-2 expression and dissociates this protein from the actin cytoskeleton within the cell
Farkas et al., Scand J Immunol 2008
:
Our study provides evidence that
NOD2 , toll-like receptor 4 (TLR4) and the adapter protein receptor interacting protein 2 (RIP2) are
induced by tumor-necrosis factor-alpha (TNF-alpha) and
interferon-gamma (IFN-gamma) in the bronchial epithelial cell line BEAS-2B
Rosenzweig et al., Invest Ophthalmol Vis Sci 2009
(Disease Models, Animal...) :
NOD2 activation
resulted in the production of
IFN-gamma within the eye
van Hoffen et al., Int Arch Allergy Immunol 2010
:
Apically added LGG, TLR2 and
NOD2 ligands, but not Bb,
enhanced IFN-gamma , IL-12 and/or TNF-alpha secretion
Hosokawa et al., J Periodontal Res 2010
(Chronic Periodontitis...) :
TNF-alpha and
IFN-gamma increased
NOD2 expression in HGFs
de Jong et al., PLoS Pathog 2012
(Salmonella Infections...) :
The interaction of Salmonella pathogen associated molecular patterns ( PAMPs ) with Toll-like receptors ( TLRs ) and
NOD-like receptors ( NLRs ) leads to inflammasome formation, activation, and recruitment of neutrophils and macrophages and the production of pro-inflammatory cytokines, most notably interleukin (IL)-6, IL-1ß, tumor necrosis factor (TNF)-a, and
interferon-gamma (IFN)-?
Swain et al., J Biosci 2013
(Bacterial Infections) :
In response to both Gram positive and Gram negative bacterial infections,
NOD1 and NOD2 receptors signalling were activated and IL-1 beta, IL-8 and
IFN- gamma were
induced