Gene interactions and pathways from curated databases and text-mining

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GSK3B — ILKAP

Text-mined interactions from Literome

Leung-Hagesteijn et al., EMBO J 2001 : Catalytically active, but not mutant ILKAP , strongly inhibited insulin-like growth factor-1 stimulated GSK3beta phosphorylation on Ser9, but did not affect phosphorylation of PKB on Ser473, suggesting that ILKAP selectively affects ILK mediated GSK3beta signalling
Kumar et al., Oncogene 2004 (Cell Transformation, Neoplastic) : Silencing of endogenous ILKAP by short interfering RNA ( siRNA ) stimulated GSK3beta phosphorylation at S9, with no effect on PKB S473 phosphorylation ... Consistent with the silencing data, ILKAP inhibition of ILK selectively inhibited S9 phosphorylation of GSK3beta without affecting S473 phosphorylation of PKB