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CDH2 — SNAI2
Text-mined interactions from Literome
Sivertsen et al., Lung Cancer 2006
(Mesothelioma...) :
Snail,
Slug and Sip1
regulate cadherin and protease expression and mediate epithelial-mesenchymal transition in cancer
Leong et al., J Exp Med 2007
(Breast Neoplasms) :
Slug was
essential for Notch mediated repression of
E-cadherin , which resulted in beta-catenin activation and resistance to anoikis
Saegusa et al., Am J Pathol 2009
(Carcinosarcoma...) :
Moreover,
Slug overexpression itself
caused repression of
E-cadherin , with subtle changes in cell morphology
Yang et al., Mol Cell Proteomics 2010
(Gastrointestinal Stromal Tumors...) :
An increase in
Slug expression by pCMV6-XL5-Slug transfection decreased E-cadherin and
increased vimentin and
N-cadherin
Shirley et al., Am J Pathol 2012
(Disease Progression...) :
Expression of exogenous
Slug in melanocytes and melanoma cells in vitro, however, suppressed E-cadherin expression,
enhanced N-cadherin expression, and stimulated cell migration and invasion