Morelli et al., Transplantation 2000
(Acute Disease) :
Here, we compared the capacity of in vitro generated normal liver immature DC and FL-treated donor liver DC to induce alloimmune CD4+ T helper ( Th ) 1/Th2 and CD8+ T cytotoxic (Tc) 1/Tc2 responses , in vitro and in vivo
Banchereau et al., Proc Natl Acad Sci U S A 2012
:
Inhibition of CD8 function on LCs inhibited cytotoxic T lymphocytes ( CTLs ) and enhanced TC2 generation