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CD69 — CD8A
Text-mined interactions from Literome
Giavedoni et al., J Virol 2000
(Simian Acquired Immunodeficiency Syndrome) :
CD8 ( + ) T cells
increased CD69 but not CD25 expression, indicating the activation of this cellular subset in PB and LN
Heinzelmann et al., Immunopharmacology 2000
:
Analysis of leukocyte subsets demonstrated that CD4 ( + ) T-cells,
CD8 ( + ) T-cell, CD19 ( + ) B-cells, CD56 ( + ) natural killer ( NK ) -cells, and CD14 ( + ) monocytes
increased the expression of
CD69 after stimulation with LPS
Fauconnier et al., Am J Pathol 2011
(Brain Ischemia...) :
Recruitment and
activation of
CD8 ( + ) T cells, and ICAM-1 and
CD69 expression were reduced in the brain of resistant mice ; however, the pulmonary inflammation and edema associated with PbA infection were still present in the absence of functional PKC-?
Freeman et al., Proc Natl Acad Sci U S A 2012
:
This study identifies several unexpected cytokine combinations that synergize to induce antigen independent IFN? production and
CD69 up-regulation by
CD8 ( + ) T cells in addition to cytokines that exhibit differential regulatory functions, with the ability to either enhance or inhibit T-cell IFN? production, depending on which cytokine partner is present
Lim et al., Mol Cells 1998
:
However, stimulation of
CD8-Igbeta can
induce activation of
CD69 surface expression and IL-2 gene expression equivalent to the level by CD8-Igalpha and CD8-zeta without induction of the tyrosine phosphorylation of intracellular signaling molecules