Gene interactions and pathways from curated databases and text-mining

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CA2 — STX12

Text-mined interactions from Literome

Ohyama et al., J Neurosci 2002 : These results indicate that the Ca2+/ATP dependent binding of CaMKII to syntaxin is an important process in the regulation of exocytosis
Zhang et al., Neuron 2002 (Calcium Signaling...) : Synaptotagmin is a proposed Ca2+ sensor on the vesicle for regulated exocytosis and exhibits Ca2+ dependent binding to phospholipids, syntaxin , and SNAP-25 in vitro, but the mechanism by which Ca2+ triggers membrane fusion is uncertain
Ubach et al., EMBO J 1998 : The first C2-domain of synaptotagmin I is believed to play a key role in neurotransmitter release via its Ca2+ dependent interactions with syntaxin and phospholipids
Sugimori et al., Neuroscience 1998 (Synaptic Transmission) : A polyclonal antibody, raised against the squid ( Loligo pealei ) syntaxin I, inhibited Ca2+ dependent interaction of syntaxin with synaptotagmin C2A domain in vitro
Shao et al., Biochemistry 1998 : The C2A domain of synaptotagmin I is believed to play a key role in neurotransmitter release through its Ca2+ dependent interactions with syntaxin and phospholipids